FOR RESEARCH PURPOSES ONLY
CJC-1295 with DAC is a research peptide and not approved by any medical board.
Overview
CJC-1295 is a tetrasubstituted 30-amino acid peptide hormone invented by ConjuChem, a biotechnology company in Canada. CJC-1295 primarily functions as a growth hormone releasing hormone analog. The way these peptides are engineered, its half life has been increased from a less as 7 minutes to greater than 7 days. Protecting groups around the amino acids of GHRH which are liable to enzymatic reaction are used to accomplish this life. With extremely long half life, the use of CJC-1295 once per weak is quite reasonable to get outstanding results. ½ dosages twice in a week are ideal to keep serum levels high. Also CJC-1295 peptide is helpful in promoting deep sleep which is a portion of sleep responsible for maximum muscle growth and retention.
Molecular Make-up of CJC-1295
Product Name – CJC-1295 Acetate
Synonyms – CJC-1295
Molecular Formula – C152H252N44O42
Sequence – Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg–NH2
Molecular Weight – 3367.97
CAS – 863288-34-0
Benefits
•Has the ability to bioconjugate with serum albumin to increase its half life and therapeutic window.
•CJC-1295 helps in promoting slow wave sleep. It is also known as deep sleep which is the part of sleep responsible for maximum muscle growth and memory retention level.
•Also it is beneficial in treating visceral fat deposits in obese AIDS patients and increasing levels of exogenous HGH to increase fat loss.
Recommended Dosage
Single dose of 60 ug/kg of CJC-1295 results in elevated levels of growth hormone while maintaining the GH secretion. However a dose of 30 ug/kg of CJC-1295 given weekly is ideal in maintaining the level of growth hormone.
Coversion factor 100mcg = 0.10mg = 10 units.
About the Formation, Uses and Benefits of CJC-1295 DAC Peptide
Over a period of time, science has shown an amazing growth in the field of medicine to let people live a better life with better health. Among those inventions is the invention of peptides which is targeted towards providing a solution to several health issues with human beings. There are various types of peptides available in the market having their specific use in the life of a person. Here in this article, we are going to talk about the CJC-1295 DAC peptide in particular, regarding its formation, molecular make up, uses and benefits, ideal dose and various other major aspects that one should know before using this peptide for effective results.
Basically CJC-1295 is a long acting growth hormone releasing hormone (GHRH) analog. GHRH, also known as growth hormone releasing factor or somatocrinin, is 44-amino acid peptide hormone which is produced by the arcuate nucleus in the hypothalamus. It stimulates secretion of growth hormone from the pituitary gland and is released in a pulsatile manner to ultimately stimulate pulsatile release of growth hormone. This pulsatile release in various peptides is the root cause for half life of the peptide due to an enzyme called dipeptidylaminopeptidase IV (DPP-IV). Thus the need for increasing the life and bioavailability of peptide compelled pharmaceutical companies to come up with technologies like PEGylation to make peptides even more effective.
Thus CJC-1295 which is a synthetic modification of GHRH with D-Ala, Gln, Ala, and Leu substitutions at positions 2, 8, 15, and 27 respectively, is applied with Drug Affinity Complex (DAC) technology to its GHRH to increase its half-life. CJC-1295 DAC peptide carefully and covalently combines to circulate albumin after subcutaneous (SC) administration leading to lengthen its half life from seven minutes to more than seven days. With the help of highly effective bioconjugation process, hardly I % of CJC-1295 remain unreacted in vivo and CJC-1295 molecule attach itself to albumin easily for prolong half-life. There are several benefits that can be assured with CJC-1295 DAC after conducting its effective test on mice in clinical lab.
Its main function is to increase protein synthesis and stimulate new muscle tissue growth. It effectively curbs growth hormone (GH) deficiency in children to let them grow normally. CJC-1295 DAC leads to an increase in muscle mass and also adds to physical strength. It is also helpful in controlling skin aging and effective in reducing wrinkles. CJC-1295 DAC leads to re-growth of internal organs atrophied with age and result in hyperplasia to increase the number of muscle cells. Besides there are other benefits like increased bone density, strong immunity, faster recovery from injuries and lipolysis promotion to reduce body fat. As per dose recommendation, it is tested that a dose of 30 or 60 µg/kg is ideal to increase GH and insulin like growth factor (IGF-1) in healthy adults. Also due to long half-life and stability, taking CJC-1295 DAC 1-2 times per week would do the required job.
All peptides are sold as research peptides
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